Effect of photobiomodulation on mitochondrial dynamics in peripheral nervous system in streptozotocin-induced type 1 diabetes in rats

There is no effective treatment to halt peripheral nervous system damage in diabetic neuropathy. Mitochondria have been at the center of discussions as important factors development neuropathy diabetes. Photobiomodulation has gaining clinical acceptance it shows beneficial effects on a variety disorders. In this study, photobiomodulation (904 nm, 45 mW, 6.23 J/cm2, 0.13 cm2, 60 ns pulsed time) mitochondrial dynamics were evaluated an adult male rat experimental model streptozotocin-induced type 1 Results presented here indicate that could role preventing or reversing dysfunction course showed its modulating protein expression mitofusin 2 and dynamin-related sciatic nerve dorsal root ganglia neurons diabetes rats.